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HESI A2 Exam Overview
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HESI Anatomy and Physiology Practice Test 1

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Question 1 of 20

1. Question
Which type of cellular connection is characterized by openings in adjacent animal cells for intercellular exchange to take place?
- a. Desmosomes
- b. Tight Junctions
- c. Gap Junctions
- d. Plasmodesmata
- e. Molecular Anchoring
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Question 2 of 20

2. Question
Which of the following would be a direct result of lipid depletion in the human body?
- a. The increase in the amount of proteins secreted in the body.
- b. The decrease in the amount of estrogen produced.
- c. The decrease in the permeability of the cellular membrane.
- d. The transfer of nuclear membrane lipids to the cytoplasm.
- e. The exchange of cytoplasmic lipids with membrane bound proteins.
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Question 3 of 20

3. Question
The engulfing of large particles into the cell is referred to as ____________?
- a. Phagocytosis
- b. Pinocytosis
- c. Exocytosis
- d. Cellular Respiration
- e. Active Transport
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Question 4 of 20

4. Question
Which of the following would be a categorized as a flat bone?
- a. Vertebrae
- b. Metatarsals
- c. Femur
- d. Scapula
- e. Mandible
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Question 5 of 20

5. Question
What type of joint is present in the elbow?
- a. Hinge joint
- b. Saddle joint
- c. Gliding joint
- d. Pivot joint
- e. Ball and socket joint
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Question 6 of 20

6. Question
In order for the actin filaments to bind to the myosin head, what must occur first?
- a. The sarcomere has to shorten.
- b. Calcium ions must bind to troponin molecules.
- c. Tropomyosin has to attach to the actin binding sites.
- d. Magnesium ions must be released by the sarcoplasmic reticulum.
- e. The Z line has to be lengthened to expose the actin binding site.
Correct

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Question 7 of 20

7. Question
What is the primary function of melatonin?
- a. To produce pigment for the skin.
- b. To regulate the fight or flight response.
- c. To regulate sleep/wake cycles.
- d. To stimulate protein synthesis.
- e. Initiates sperm and egg maturation.
Correct

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Question 8 of 20

8. Question
The limbic system of the brain is responsible for the regulation of ___________?
- a. Vision
- b. Emotion
- c. Motor movement
- d. Speech production
- e. Metabolic processes
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Question 9 of 20

9. Question
Which is a bodily reaction to the fight or flight response?
- a. Pupil dilation
- b. Vasoconstriction
- c. Increase perspiration
- d. Decrease gastric motility
- e. All of the above
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Question 10 of 20

10. Question
What area(s) of the brain are the most affected if a person is unable to understand written or verbal speech?
- a. Weirnecke’s area
- b. Broca’s area
- c. Occipital lobe
- d. Parietal lobe
- e. A and B
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Question 11 of 20

11. Question
The release of prolactin during breastfeeding is an example of __________________?
- a. Negative feedback
- b. Positive feedback
- c. Gene regulation
- d. Protein synthesis
- e. Cell permeability
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Question 12 of 20

12. Question
What would result following an injury to the phrenic nerve?
- a. An inability to stand
- b. An irregular heart rate
- c. An inability to control breathing
- d. An increase in body temperature
- e. An increase in facial spasms
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Question 13 of 20

13. Question
Which sequence outlines the correct flow of blood through the heart?

I. Blood exits through the aorta.

II. Blood exits through the pulmonary artery to go to the lungs.

III. Blood enters the left atrium.

IV. Blood passes through the mitral valve.

V. Blood enters the right atrium.
- a. II, III, V, IV, I
- b. I, II, III, IV, V
- c. III, IV, V, I, II
- d. V, II, III, IV, I
- e. V, III, II, I, IV
Correct

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Question 14 of 20

14. Question
What valve is responsible for preventing the backflow of blood from the right ventricle to the right atrium?
- a. Mitral valve
- b. Tricuspid valve
- c. Semilunar valve
- d. Aortic valve
- e. Pulmonary valve
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Question 15 of 20

15. Question
The right side of the heart is associated with which type of circulation?
- a. Pulmonary circulation
- b. Aortic circulation
- c. Ventricular circulation
- d. Systemic circulation
- e. Myocardial circulation
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Question 16 of 20

16. Question
During exhalation, the diaphragm does which of the following?
- a. Relaxes and lifts
- b. Relaxes and lowers
- c. Contracts and lifts
- d. Contracts and lowers
- e. Does not move
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Question 17 of 20

17. Question
The autoimmune disease, multiple sclerosis is characterized by the degradation of what?
- a. Proteins
- b. Carbohydrates
- c. Myelin Sheath
- d. Dendrites
- e. Phospholipids
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Question 18 of 20

18. Question
Respiration rates are regulated by which of the following?
- a. Increasing levels of oxygen
- b. Increasing levels of nitrogen
- c. Increasing levels of carbon dioxide
- d. Decreasing levels of oxygen
- e. Decreasing level of carbon dioxide
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Question 19 of 20

19. Question
What lobe of the brain is responsible for processing olfactory information?
- a. Frontal
- b. Parietal
- c. Occipital
- d. Temporal
- e. Corpus Callosum
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Question 20 of 20

20. Question
Which two bones make up the structure of the lower leg?
- a. Radius and Ulna
- b. Femur & Patella
- c. Metatarsal & Tarsal
- d. Sternum & Clavicle
- e. Fibula & Tibia
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HESI Anatomy and Physiology Practice Test 1

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